Clinical Progress of Biopharmaceutical Plants

Biopharmaceutical plants follow the concepts for producing efficient medicines by pharmaceutical engineering. In biotechnology they mainly use the concepts of latest and developed technology. To prepare efficient medicines an important source of raw-materials are used for some of the living organisms' like plant sources. This article is all about the clinical success of the biopharmaceutical industries.

The therapeutic proteins demand is increasing every day because of their ability to cure more dangerous diseases. Biotechnology is growing at a fast phase since it was introduced about 20 years ago and it is still growing. A tremendous profit has been attained from the red-blood-cell stimulating agents, growth hormones, insulin etc. Arthritis, multiple sclerosis and many foundling diseases can be cured by the recombinant proteins. These restorative proteins are blessing for all human beings.

Biotechnology

In the world market around 80 biopharmaceutical plants are available and at different clinical levels around 500 are under the developing stage. The recombinant antibodies (rAbs) and their products are very important of all the biopharmaceutical available today. Improvements in biotechnology have implemented for the development of human antibodies, with redefined therapeutic potential. Therapeutic monoclonal antibodies (Mabs) also have tremendous ability and for the total production of the biopharmaceuticals it can contribute around 40%. These biopharmaceutical has the potential to fight the most dangerous diseases like cancer.

Clinical Progress of Biopharmaceutical Plants

Biopharmaceutical plants have absolute capability for effective drug production. These medicines are capable in fighting diseases and also cost-effective. Therefore, these plants gained lot of clinical success in a very limited period. We can say that the use of botanical sources by these plants have bought a remarkable change in the medical world as the medicines developed by these sources are more efficient and also free from all sorts of side effects. These medicines can cure all the common as well as crucial diseases.

Clinical Progress of Biopharmaceutical PlantsX-Men Evolution: Season 1, Episode 5 Video Clips. Duration : 21.03 Mins.

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For more information on Pharmaceutical engineering and the benefits of Biopharmaceutical plants please visit the mentioned website

Malunggay's Moringa Oil Seen as Biofuel Source

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As the Philippines seeks better ways to use its resources in combating climate change, a new discovery by a Filipino biotechnology company based in the U.S. has tapped a wonder plant in the country as a source of biofuel.

Malunggay, scientifically known as Moringa oleifera Lamk, which is widely grown in the Philippines and is considered one the world's most useful plants, is found as a good source of Moringa oil. This oil is believed to be a biofuel source.

SECURA International announced that malunggay oil is being tapped by the North American Biofuels Inc. (NABI) since January as possible raw material for biodiesel production. As a result, the former is currently growing malunggay in 500,000-hectare farmland to meet the demands of NABI.

Since malunggay can easily be grown in the country, SECURA International president Danny Manayaga encouraged the Filipino farmers to take advantage of the situation in meeting the demands of the world for the Moringa oil supply to be used as biodiesel.

Manayaga said this business is sustainable since the market is very accessible. Currently, there are 165 marketing companies in the U.S. for biodiesel using soybean oil as raw material. It is expected that in the next 50 years, Japan and Korea will be the biggest markets of Moringa oil for their automobiles that will use biodiesel.

Others might be thinking of the real viability of Moringa oil as biodiesel. But the NABI has already authenticated that it has passed the biofuels standards. This means doubts of whether this can truly be used are over.

Earlier, the Philippine government is endorsing jatropha as a source of biofuel. However, Manayaga said Moringa oil is more useful that jatropha. What makes malunggay better than the jatropha is that malunggay is 100 percent usable; all parts are biodegradable. Unlike jatropha, it has a toxic part. Once its oil is extracted, the left-over part becomes a nuclear waste according to the findings.

With malunggay as a biofuel source in the Philippines, the country may in some way help other countries reduce the impact of global warming by sharing the benefits of Moringa oil.

Maynard Joseph Delfin finished AB Journalism (cum laude) at the University of Santo Tomas. He has worked as book editor, deskman, copy editor and research and publications officer in leading publishing and research companies in the Philippines.

Biotechnology Timeline: Important Events And Discoveries In Biotechnology

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1977:

The Age of biotechnology arrives with "somatostatin" - a human growth hormone-releasing inhibitory factor, the first human protein manufactured in bacteria by Genentech, Inc. A synthetic, recombinant gene was used to clone a protein for the first time.

1978:

Genentech, Inc. and The City of Hope National Medical Center announce the successful laboratory production of human insulin using recombinant DNA technology. Hutchinson and Edgell show it is possible to introduce specific mutations at specific sites in a DNA molecule.

1979:

Sir Walter Bodmer suggests a way of using DNA technology to find gene markers to show up specific genetic diseases and their carriers. John Baxter reports cloning the gene for human growth hormone.

1980:

The prokaryote model, E. coli, is used to produce insulin and other medicine, in human form. Researchers successfully introduce a human gene - one that codes for the protein interferon- into a bacterium. The U.S. patent for gene cloning is awarded to Cohen and Boyer.

1981:

Scientists at Ohio University produce the first transgenic animals by transferring genes from other animals into mice. The first gene-synthesizing machines are developed. Chinese scientists successfully clone a golden carp fish.

1982:

Genentech, Inc. receives approval from the Food and Drug Administration to market genetically engineered human insulin. Applied Biosystems, Inc. introduces the first commercial gas phase protein sequencer.

1983:

The polymerase chain reaction is invented by Kary B Mullis. The first artificial chromosome is synthesized, and the first genetic markers for specific inherited diseases are found.

1984:

Chiron Corp. announces the first cloning and sequencing of the entire human immunodeficiency virus (HIV) genome. Alec Jeffreys introduces technique for DNA fingerprinting to identify individuals. The first genetically engineered vaccine is developed.

1985:

Cetus Corporation's develops GeneAmp polymerase chain reaction (PCR) technology, which could generate billions of copies of a targeted gene sequence in only hours. Scientists find a gene marker for cystic fibrosis on chromosome number 7.

1986:

The first genetically engineered human vaccine - Chiron's Recombivax HB - is approved for the prevention of hepatitis B. A regiment of scientists and technicians at Caltech and Applied Biosystems, Inc. invented the automated DNA fluorescence sequencer.

1987:

The first outdoor tests on a genetically engineered bacterium are allowed. It inhibits frost formation on plants. Genentech's tissue plasminogen activator (tPA), sold as Activase, is approved as a treatment for heart attacks.

1988:

Harvard molecular geneticists Philip Leder and Timothy Stewart awarded the first patent for a genetically altered animal, a mouse that is highly susceptible to breast cancer

1989:

UC Davis scientists develop a recombinant vaccine against the deadly rinderpest virus. The human genome project is set up, a collaboration between scientists from countries around the world to work out the whole of the human genetic code.

1990:

The first gene therapy takes place, on a four-year-old girl with an immune-system disorder called ADA deficiency. The human genome project is formally launched.

1991:

Mary-Claire King, of the University of California, Berkeley, finds evidence that a gene on chromosome 17 causes the inherited form of breast cancer and also increases the risk of ovarian cancer. Tracey the first transgenic sheep is born.

1992:

The first liver xenotransplant from one type of animal to another is carried out successfully. Chiron's Proleukin is approved for the treatment of renal cell cancer.

1993:

The FDA declares that genetically engineered foods are "not inherently dangerous" and do not require special regulation. Chiron's Betaseron is approved as the first treatment for multiple sclerosis in 20 years.

1994:

The first genetically engineered food product, the Flavr Savr tomato, gained FDA approval. The first breast cancer gene is discovered. Genentech's Nutropin is approved for the treatment of growth hormone deficiency.

1995:

Researchers at Duke University Medical Center transplanted hearts from genetically altered pigs into baboons, proving that cross-species operations are possible. The bacterium Haemophilus influenzae is the first living organism in the world to have its entire genome sequenced.

1996:

Biogen's Avonex is approved for the treatment of multiple sclerosis. The discovery of a gene associated with Parkinson's disease provides an important new avenue of research into the cause and potential treatment of the debilitating neurological ailment.

1997:

Researchers at Scotland's Roslin Institute report that they have cloned a sheep--named Dolly--from the cell of an adult ewe. The FDA approves Rituxan, the first antibody-based therapy for cancer.

1998:

The first complete animal genome the C.elegans worm is sequenced. James Thomson at Wisconsin and John Gearhart in Baltimore each develop a technique for culturing embryonic stem cells.

1999:

A new medical diagnostic test will for the first time allow quick identification of BSE/CJD a rare but devastating form of neurologic disease transmitted from cattle to humans.

2000:

"Golden Rice," modified to make vitamin A. Cloned pigs are born for the first time in work done by Alan Coleman and his team at PPL, the Edinburgh-based company responsible for Dolly the sheep.

2001:

The sequence of the human genome is published in Science and Nature, making it possible for researchers all over the world to begin developing genetically based treatments for disease.

2002:

Researchers sequence the DNA of rice, and is the first crop to have its genome decoded.

2003:

The sequencing of the human genome is completed.

Biotechnology HQ http://biotechnology-hq.com/ articles and information about the science of biotechnology.

Low Cost Things to Do With Kids - Work a Puzzle Together

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Working puzzles is a very good indoor activity, especially appropriate if the weather is rainy or cold and not suitable for playing outside. Puzzles are widely available at toy stores and specialty shops and are typically inexpensive. It is important to make sure the puzzle is age appropriate, not too difficult so that your child get frustrated and loses interest quickly, and not so easy that your son or daughter is quickly bored. If you want the activity to be more educational, choose a puzzle with a theme: the world, United States, the solar system.

I think it is best not to help out too much, but rather let your son or daughter work on the puzzle with only a little assistance from you. If you see that your child is having trouble, you can scratch your head as you pretend to look for a piece, and maybe occasionally nudge it into view. For young kids, in the range of 3-6 yeas of age, try to find a puzzle that can be completed in 5 minutes or less; this will approximately match the amount of time a youngster can focus in a sitting. To stay within this time window, the puzzle should have no more than about 20-30 pieces.

One of my favorite puzzles for kids who are slightly older, about 5 years old and up, is a puzzle of the United States of America with pieces in the shape of the states. What a great way to learn about the 50 states while doing something fun at the same time!

David Rozzell blogs at http://rozzell.com about things to do with your kids that are fun, help build strong relationships, and cost little or nothing to do.

Biotechnology - Fast Emerging Sector of India

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Biotechnology is considered to be a quickly emerging and far-reaching technology. It's a branch of science that may play a major role in the development and growth of India. Biotechnology refers to any technological application that uses biological systems and forms in a governable manner, to not only produce new and useful processes or products but also modify the existing ones. It benefits both mankind and other life forms, such as microorganisms. Besides, biotechnology helps maintain an optimum ecological balance by lowering the amount of hydrocarbons and controlling pollution.

Biotechnology in India is one of the most rapidly growing knowledge-based sectors. Today, it's being increasingly used to design and develop unique, improved varieties of pharmaceutical products, crops, fertilizers, processed foods, a plethora of chemicals, cosmetics, growth enhancers, health care aids, and environment-related substances. The biotech segment in India has been making fast strides on the world platform. India is currently producing and marketing many therapeutic biotech drugs and vaccines. From 2005-2006, the Indian biotech sector recorded an impressive revenue of approximately US$ 1.07 billion and registered a 36.55% growth.

India has diverse biological resources. Biotechnology offers opportunities to convert these resources into employment opportunities and economic wealth. Several factors create an impetus for India to produce excellent capabilities in the domain of biotechnology. These factors include a strong pool of scientists and engineers, a large reservoir of scientific human resources, affordable manufacturing capabilities, numerous medical colleges, educational and training institutes providing diplomas and degrees in biotechnology, a large number of national research laboratories engaging thousands of scientists, fast developing clinical capabilities, and a vibrant drugs and pharmaceutical industry.

The Department of Biotechnology (DBT) in India is regulated by the Ministry of Science and Technology and is a top authority responsible for the development of the biotech industry. This department is responsible for planning, promoting, and organizing different biotechnological activities and programs in India. It also offers grants to universities, national research laboratories, and research foundations associated with biotechnology-related activities.

The key responsibilities of the DBT include:

1. Promoting large-scale use of biotechnology
2. Acting as a government agent for importing fresh recombinant DNA-based biotechnological processes, technologies, and products
3. Building infrastructure facilities to aid R&D and production
4. Initiating technical and scientific efforts associated with biotechnology
5. Promoting international collaborations to expound the knowledge base of the biotech sector in India
6. Providing bio-safety guidelines for laboratory research, applications, and production
7. Serving as a nodal agency for collecting and disseminating biotechnology-related information

Furthermore, the Indian government has set up the National Bio-Resource Development Board (NBDB) under the department to determine the broad-policy framework for efficient use of biotechnological research and development.

The key functions of this board include:

1. Promoting how bio-resources add value and strengthening bioinformatics
2. Formulating predictive groupings of biological resources via well-developed molecular lineages
3. Providing efficient conservation strategies for bio-resources with potential economic and scientific value
4. Promoting the application of biological software in pathogens' and agricultural pests' management
5. Training and teaching human resources towards achieving all these objectives

The Indian government is also establishing many biotech parks and incubators. Some existing biotech parks/incubation centers are in Uttar Pradesh, Hyderabad, Kerala, Himachal Pradesh, and Bangalore.

With so many measures being adopted to promote biotechnology, the Indian biotech sector is set to flourish, and it can revolutionize agriculture, industrial processing, health care, and environmental sustainability.

The government of India has taken several initiatives to attract foreign investments in India. Not only foreign establishments but also entrepreneurs from India can reap the benefits of the growing Indian Market.

Gene Wize Life Sciences - Get Your Review About Gene Wize Here

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Gene Wize is a cutting edge biotechnology company that is making every individual re-think about what nutritional supplements are good for them and which ones are not.

GeneWize claims that DNA doesn't lie and they have proved it time and time again by taking a person's DNA and then customizing a nutritional program specific for their body and its needs.

By simply wiping 2 cotton swabs inside your mouth, that is how you will gather your own DNA so that Gene Wize Life Sciences can analyze your DNA in their state of the art biotechnology laboratory center and then customize your very own nutritional supplements that are made ONLY for you.

Never, in the health and wellness industry, have we seen anything like this before. There is no other company in the world that does this. GeneWize's technology to analyze a person's DNA is a PATENT product.

Now, behind GeneWize's incredible and revolutionary product lies a great business opportunity that will take the lead in the home based network marketing industry. GeneWize brings something very unique to the market place that is not found anywhere else.

Gene Wize has also made its revolutionizing product very affordable for just about anyone who want to have a DNA customized nutrition made specifically for them.

In closing, after doing a throughout review on GeneWize Life Sciences and its state of the art product, I and many people are very excited that now we are able to give our body what it EXACTLY needs. That is very exciting.

For more information on Gene Wize and their cutting edge product line please visit my GeneWize review website Here [http://www.geneteamreview.com] Tal Fighel is an accomplished internet entrepreneur and marketer. For more information on Tal, check out his website Here [http://www.geneteamreview.com]

Tapping the Untapped and Taming the Untamed

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Modern age has witnessed and is going through many changes. New discoveries are being made in every field. Biotechnology is making new breakthroughs in farming. In fact using farmer friendly insects and animals in farming is not a new idea. Since olden times, people have known about creatures that helped the farmers in one way or the other. The idea of using animal wastes in the form of manure is very old and useful. This is only one-way to show how animals prove helpful to people.

Insects are both useful as well as harmful to crops. The aphids are very minute insects and are responsible for bringing down the yield of many crops and fruit. They are minute winged creatures that suck sap or juices from the soft parts of plants like newly emerged shoots and fresh leaves. They suck them dry and leaves begin to curl and turn yellow or brown. But nature has provided useful insects like ladybirds and mantids, which feed on these pests and keep their numbers in check. A ladybird is a small rounded shaped insect from beetle family.It is usually yellowish red or deep red in colour with dark black spots on its body. It is a voracious feeder on aphids. A single ladybird forages on hundreds of aphids in a single day. The nymphs in ladybirds are even more active feeders. The increased use of chemicals and pesticides is reducing the numbers of useful insects. The pesticides may kill harmful insects but they also kill useful insects in large numbers. It is better to avoid the use of chemicals for pest control. If we learn to observe the insect activities. We come to know how useful they are to humans. Some idea may at this point of time seem fantastic and weird but they can be put to practice and may be they become very common in future. There is no harm in trying new things.

It is a fantastic idea to imagine that creatures supposed to have less developed brains can be trained to behave in a certain way. It is making things work the way they can't. It is quite weird to think of scary creatures like preying mantids become useful to serve human needs. It would be great idea to make these creatures work at our will or when and where we need them. In nature, it is common that many creatures prey upon other such creatures, which are understood to be harmful to humans. In case of plants as a major source of food for humans, this becomes a very important issue. Aphids and other leaf-eating insects do great harm to plants serving as food for humans and cattle.

An experiment to mould the behaviour of wasps to serve human needs can be performed. There are ground dwelling wasps that capture, kill and feed upon aphids and caterpillars harming human interests. A colony of such wasps near you can become a place of observation and experimentation. Try to capture pest like an aphid. Hook it onto the tip of a slender twig or stick long enough to keep you safe from too close a contact with the busy ground colonising wasps. Try to draw the bait, close to the busy entrance. The baited aphid will attract the attention of the wasps hovering about. It will be picked up and carried inside into the colony as food.

Try the same with different types of pests you consider harmful to plants. Gradually, you can try a small branch laden with pests on leaves. Bring it close to the entrance; the wasps will gladly do the job. Try to gradually increase the distance between the offered bait and the wasp nest. With passage of time, wasps will learn to detect the presence of aphids and other pests even at distance around them. You will find plants and leaves picked neat and cleaned of any pests. This experiment can serve to abandon the notorious use of chemical pesticides and adopt biological means of pest control and save the environment. It is high time to pit creatures against creatures.

As the world is witnessing more and more toxics being added to environment it is high time we pay back what we have taken away from nature. If not all we must be considerate in paying back some so that there is nothing to lose. It is time to re-create, re-define and re-live life which is more compatible to natural environment. When we cure nature it cures us and serves our needs. Helping nature is helping us.

Regards
Harjinder Singh